Wissenschaftliche Publikationen

  • Behringer, A.; Stoimenovski, D.; Porsch, M.; Hoffmann, K.; Behre, G.; Grosse, I.; Kalinski, T.; Haybaeck, J.; Nass, N. Relationship of micro-RNA, mRNA and eIF Expression in Tamoxifen-Adapted MCF-7 Breast Cancer Cells: Impact of miR-1972 on Gene Expression, Proliferation and Migration. Biomolecules2022, 12, 916. https://doi.org/10.3390/biom12070916
    Abstract: https://www.mdpi.com/2218-273X/12/7/916
    PDF Version: https://www.mdpi.com/2218-273X/12/7/916/pdf
  • Czapiewski P, Cornelius M, Hartig R, Kalinski T, Haybaeck J, Dittmer A, Dittmer J, Ignatov A, Nass N. Virchows Arch. 2022 Jan 12. doi: 10.1007/s00428-021-03238-8. Online ahead of print.PMID: 35020071
  • Peter Chen, MD, Gerhard Behre, MD, Corey Hebert, MD, Princy Kumar, MD, Lisa Farmer Macpherson, MSc, Peita Louise Graham-Clarke, PhD, Inmaculada De La Torre, MD PhD, Russell M Nichols, PharmD, Matthew M Hufford, PhD, Dipak R Patel, MD PhD, , April N Naegeli, DrPH,  Bamlanivimab and etesevimab improve symptoms and associated outcomes in ambulatory patients at increased risk for severe COVID-19: results from the placebo-controlled double-blind Phase 3 BLAZE-1 trial, Open Forum Infectious Diseases, 2022;, ofac172. Online on academic.oup.com
  • Reschke R, Zimmerlich S, Döhring C, Behre G, Ziemer M.Effective Extracorporeal Photopheresis of Patients with Transplantation Induced Acute Intestinal GvHD and Bronchiolitis Obliterans Syndrome. Biomedicines. 2022 Aug 4;10(8):1887. doi: 10.3390/biomedicines10081887. PMID: 36009436; PMCID: PMC9405770.
  • Norbert Nass, Florian Stelzner, Stephan Bernhart, Gerhard Behre
    Expression and function of eukaryotic initiation factors in CEBPA-mutated acute myeloid leukemia; Conference: XI-ZOMES, PCI-complexes - Determining Cell Physiology by Setting the Course in Protein Turnover,  Magdeburg, Germany, September 2022

  • Krüger WH, Hirt C, Basara N, Sayer HG, Behre G, Fischer T, Grobe N, Maschmeyer G, Neumann T, Schneidewind L, Niederwieser D, Dölken G, Schmidt CA. Allogeneic stem cell transplantation for mantle cell lymphoma-update of the prospective trials of the East German Study Group Hematology/Oncology (OSHO#60 and #74). Ann Hematol. 2021 Jun;100(6):1569-1577. doi: 10.1007/s00277-021-04506-y. Epub 2021 Apr 8. PMID: 33829299; PMCID: PMC8116228.
  • Pieper W, Ignatov A, Kalinski T, Haybaeck J, Czapiewski P, Nass N. The predictive potential of Neuronatin for neoadjuvant chemotherapy of breast cancer. Cancer Biomark. 2021 May 28. doi: 10.3233/CBM-203127. Epub ahead of print. PMID: 34092612.
  • Vo DK, Engler A, Stoimenovski D, Hartig R, Kaehne T, Kalinski T, Naumann M, Haybaeck J, Nass N. Interactome Mapping of eIF3A in a Colon Cancer and an Immortalized Embryonic Cell Line Using Proximity-Dependent Biotin Identification. Cancers (Basel). 2021 Mar 14;13(6):1293. doi: 10.3390/cancers13061293. PMID: 33799492; PMCID: PMC7999522.
  • Monoclonal antibodies therapy for Covid-19 - Experiences at a regional hospital. Judith Pannier, Norbert Nass, Gerhard Behre. doi: https://doi.org/10.1101/2021.09.22.21263488 
  • The impact of G protein-coupled oestrogen receptor 1 on male breast cancer: a retrospective analysis. Jan-Hendrik Maiwald, Susanne Sprung, Piotr Czapiewski, Wiebke Lessel, Anna Scherping, Dirk Schomburg, Markus Plaumann, Bartłomiej Tomasik, Gerhard Behre, Johannes Haybaeck, Atanas Ignatov, Holm Eggemann, Norbert Nass. Contemp Oncol (Pozn) 2021; 25 (3): 204–212. DOI: https://doi.org/10.5114/wo.2021.11001
  • Monoklonale Antikörper COVID-19-Therapie – Erfahrungen im Klinikum Dessau, in: JOURNAL ONKOLOGIE 12/2021, von PD Dr. rer. nat. habil. Norbert Naß und Dr. med. Judith Pannier und Prof. Dr. med. Gerhard Behre

  • Kubasch AS, Franke GN, Aldaoud A, Weibl K, Jentzsch M, Sabri O, Horny HP, Fend F, Behre G, Platzbecker U, Vucinic V. Allogeneic Hematopoietic Stem Cell Transplantation in a Rare Case of Tonsillar Mast Cell Sarcoma. Front Oncol. 2020 Feb 28;10:219. doi: 10.3389/fonc.2020.00219. PMID: 32181155; PMCID: PMC7059127.
  • Vucinic V, Jentzsch M, Schwind S, Bach E, Leiblein S, Remane Y, Rieprecht S, Otto S, Kubasch AS, Behre G, Cross M, Platzbecker U, Franke GN. Case Report: Allogeneic Stem Cell Transplantation Following Induction With CPX-351 in Patients With Acute Myeloid Leukemia Is Feasible. Front Oncol. 2020 Sep 16;10:1746. doi: 10.3389/fonc.2020.01746. PMID: 33042819; PMCID: PMC7526474.
  • Jentzsch M, Bill M, Grimm J, Schulz J, Schuhmann L, Brauer D, Goldmann K, Wilke F, Franke GN, Behre G, Pönisch W, Vucinic V, Niederwieser D, Platzbecker U, Schwind S. High expression of the stem cell marker <i>GPR56</i> at diagnosis identifies acute myeloid leukemia patients at higher relapse risk after allogeneic stem cell transplantation in context with the CD34+/CD38- population. Haematologica. 2020 Oct 1;105(10):e507. doi: 10.3324/haematol.2019.229260. PMID: 33054093; PMCID: PMC7556671.
  • Scheifele C, Zhu Q, Ignatov A, Kalinski T, Nass N. Glyoxalase 1 expression analysis by immunohistochemistry in breast cancer. Pathol Res Pract. 2020 Dec;216(12):153257. doi: 10.1016/j.prp.2020.153257. Epub 2020 Oct 18. PMID: 33142109.
  • Chen Q, Yang B, Nass N, Schatz C, Haybaeck J. Impact of Eukaryotic Translation Initiation Factors on Breast Cancer: Still Much to Investigate. Cancers (Basel). 2020 Jul 21;12(7):1984. doi: 10.3390/cancers12071984. PMID: 32708122; PMCID: PMC7409344.
  • Zjablovskaja P, Kardosova M, Danek P, Angelisova P, Benoukraf T, Wurm AA, Kalina T, Sian S, Balastik M, Delwel R, Brdicka T, Tenen DG, Behre G, Fiore F, Malissen B, Horejsi V, Alberich-Jorda M. Correction to: EVI2B is a C/EBPα target gene required for granulocytic differentiation and functionality of hematopoietic progenitors. Cell Death Differ. 2019 Jan;26(1):198. doi: 10.1038/s41418-018-0146-z. Erratum for: Cell Death Differ. 2017 Apr;24(4):705-716. PMID: 29991745; PMCID: PMC6294764.
  • Grimm J, Bill M, Jentzsch M, Beinicke S, Häntschel J, Goldmann K, Schulz J, Cross M, Franke GN, Behre G, Vucinic V, Pönisch W, Lange T, Niederwieser D, Schwind S. Clinical impact of clonal hematopoiesis in acute myeloid leukemia patients receiving allogeneic transplantation. Bone Marrow Transplant. 2019 Aug;54(8):1189-1197. doi: 10.1038/s41409-018-0413-0. Epub 2018 Nov 30. PMID: 30504903.
  • Karlas T, Weiße T, Petroff D, Beer S, Döhring C, Gnatzy F, Niederwieser D, Behre G, Mössner J, Fischer J, Tröltzsch M, Wiegand J, Keim V, Franke GN. Predicting hepatic complications of allogeneic hematopoietic stem cell transplantation using liver stiffness measurement. Bone Marrow Transplant. 2019 Nov;54(11):1738-1746. doi: 10.1038/s41409-019-0464-x. Epub 2019 Feb 26. Erratum in: Bone Marrow Transplant. 2019 Mar 19;: PMID: 30809042.
  • Karlas T, Weiße T, Petroff D, Beer S, Döhring C, Gnatzy F, Niederwieser D, Behre G, Mössner J, Fischer J, Tröltzsch M, Wiegand J, Keim V, Franke GN. Author Correction: Predicting hepatic complications of allogeneic hematopoietic stem cell transplantation using liver stiffness measurement. Bone Marrow Transplant. 2019 Nov;54(11):1920. doi: 10.1038/s41409-019-0512-6. Erratum for: Bone Marrow Transplant. 2019 Nov;54(11):1738-1746. PMID: 30890767.
  • Jentzsch M, Geus U, Grimm J, Vucinic V, Pönisch W, Franke GN, Behre G, Niederwieser D, Schwind S. Pretreatment CD34<sup>+</sup>/CD38<sup>-</sup> Cell Burden as Prognostic Factor in Myelodysplastic Syndrome Patients Receiving Allogeneic Stem Cell Transplantation. Biol Blood Marrow Transplant. 2019 Aug;25(8):1560-1566. doi: 10.1016/j.bbmt.2019.03.022. Epub 2019 Mar 28. PMID: 30928626.
  • Jentzsch M, Döhring C, Linke R, Hille A, Grimm J, Pönisch W, Vucinic V, Franke GN, Behre G, Niederwieser D, Schwind S. Comparison of non-myeloablative and reduced-intensity allogeneic stem cell transplantation in older patients with myelodysplastic syndromes. Am J Hematol. 2019 Dec;94(12):1344-1352. doi: 10.1002/ajh.25636. Epub 2019 Oct 4. PMID: 31495933.
  • Jentzsch M, Bill M, Grimm J, Schulz J, Beinicke S, Häntschel J, Goldmann K, Pönisch W, Franke GN, Vucinic V, Cross M, Behre G, Lange T, Niederwieser D, Schwind S. Prognostic Impact of Blood <i>MN1</i> Copy Numbers Before Allogeneic Stem Cell Transplantation in Patients With Acute Myeloid Leukemia. Hemasphere. 2019 Feb 8;3(1):e167. doi: 10.1097/HS9.0000000000000167. PMID: 31723806; PMCID: PMC6745933.
  • Czepukojc B, Abuhaliema A, Barghash A, Tierling S, Naß N, Simon Y, Körbel C, Cadenas C, van Hul N, Sachinidis A, Hengstler JG, Helms V, Laschke MW, Walter J, Haybaeck J, Leclercq I, Kiemer AK, Kessler SM. <i>IGF2</i> mRNA Binding Protein 2 Transgenic Mice Are More Prone to Develop a Ductular Reaction and to Progress Toward Cirrhosis. Front Med (Lausanne). 2019 Sep 4;6:179. doi: 10.3389/fmed.2019.00179. PMID: 31555647; PMCID: PMC6737005.
  • Vo DH, Hartig R, Weinert S, Haybaeck J, Nass N. G-Protein-Coupled Estrogen Receptor (GPER)-Specific Agonist G1 Induces ER Stress Leading to Cell Death in MCF-7 Cells. Biomolecules. 2019 Sep 18;9(9):503. doi: 10.3390/biom9090503. PMID: 31540491; PMCID: PMC6769846.
  • Porsch M, Özdemir E, Wisniewski M, Graf S, Bull F, Hoffmann K, Ignatov A, Haybaeck J, Grosse I, Kalinski T, Nass N. Time resolved gene expression analysis during tamoxifen adaption of MCF-7 cells identifies long non-coding RNAs with prognostic impact. RNA Biol. 2019 May;16(5):661-674. doi: 10.1080/15476286.2019.1581597. Epub 2019 Mar 5. PMID: 30760083; PMCID: PMC6546408.
  • Ignatov T, Claus M, Nass N, Haybaeck J, Seifert B, Kalinski T, Ortmann O, Ignatov A. G-protein-coupled estrogen receptor GPER-1 expression in hormone receptor-positive breast cancer is associated with poor benefit of tamoxifen. Breast Cancer Res Treat. 2019 Feb;174(1):121-127. doi: 10.1007/s10549-018-5064-8. Epub 2018 Nov 26. PMID: 30478785.
  • Schmalbrock LK, Bonifacio L, Bill M, Jentzsch M, Schubert K, Grimm J, Cross M, Lange T, Vucinic V, Pönisch W, Behre G, Franke GN, Niederwieser D, Schwind S. Prognostic relevance of DNMT3A R882 mutations in AML patients undergoing non- myeloablative conditioning hematopoietic stem cell transplantation. Bone Marrow Transplant. 2018 May;53(5):640-643. doi: 10.1038/s41409-017-0060-x. Epub 2018 Jan 15. PMID: 29335621.
  • Schmidt V, Niederwieser D, Schenk T, Behre G, Klink A, Pfrepper C, Hinke A, Beelen DW, Junghanss C, Uharek L, Krüger WH, Hochhaus A, Sayer HG; East German Study Group for Hematology and Oncology (OSHO). Efficacy and safety of keratinocyte growth factor (palifermin) for prevention of oral mucositis in TBI- based allogeneic hematopoietic stem cell transplantation. Bone Marrow Transplant. 2018 Sep;53(9):1188-1192. doi: 10.1038/s41409-018-0135-3. Epub 2018 Mar 15. PMID: 29545592.
  • Krakowsky RHE, Wurm AA, Gerloff D, Katzerke C, Bräuer-Hartmann D, Hartmann JU, Wilke F, Thiede C, Müller-Tidow C, Niederwieser D, Behre G. miR-451a abrogates treatment resistance in FLT3-ITD-positive acute myeloid leukemia. Blood Cancer J. 2018 Mar 21;8(3):36. doi: 10.1038/s41408-018-0070-y. PMID: 29563490; PMCID: PMC5862828.
  • Bill M, Grimm J, Jentzsch M, Kloss L, Goldmann K, Schulz J, Beinicke S, Häntschel J, Cross M, Vucinic V, Pönisch W, Behre G, Franke GN, Lange T, Niederwieser D, Schwind S. Digital droplet PCR-based absolute quantification of pre-transplant NPM1 mutation burden predicts relapse in acute myeloid leukemia patients. Ann Hematol. 2018 Oct;97(10):1757-1765. doi: 10.1007/s00277-018-3373-y. Epub 2018 May 22. PMID: 29785446.
  • Hartmann JU, Bräuer-Hartmann D, Kardosova M, Wurm AA, Wilke F, Schödel C, Gerloff D, Katzerke C, Krakowsky R, Namasu CY, Bill M, Schwind S, Müller-Tidow C, Niederwieser D, Alberich-Jorda M, Behre G. MicroRNA-143 targets ERK5 in granulopoiesis and predicts outcome of patients with acute myeloid leukemia. Cell Death Dis. 2018 Jul 26;9(8):814. doi: 10.1038/s41419-018-0837-x. PMID: 30050105; PMCID: PMC6062564.
  • Ruhnke M, Behre G, Buchheidt D, Christopeit M, Hamprecht A, Heinz W, Heussel CP, Horger M, Kurzai O, Karthaus M, Löffler J, Maschmeyer G, Penack O, Rieger C, Rickerts V, Ritter J, Schmidt-Hieber M, Schuelper N, Schwartz S, Ullmann A, Vehreschild JJ, von Lilienfeld-Toal M, Weber T, Wolf HH. Diagnosis of invasive fungal diseases in haematology and oncology: 2018 update of the recommendations of the infectious diseases working party of the German society for hematology and medical oncology (AGIHO). Mycoses. 2018 Nov;61(11):796-813. doi: 10.1111/myc.12838. Epub 2018 Sep 3. PMID: 30098069.
  • Hilger N, Mueller C, Stahl L, Mueller AM, Zoennchen B, Dluczek S, Halbich C, Wickenhauser C, Gerloff D, Wurm AA, Behre G, Kretschmer A, Fricke S. Incubation of Immune Cell Grafts With MAX.16H5 IgG1 Anti-Human CD4 Antibody Prolonged Survival After Hematopoietic Stem Cell Transplantation in a Mouse Model for Fms Like Tyrosine Kinase 3 Positive Acute Myeloid Leukemia. Front Immunol. 2018 Oct 22;9:2408. doi: 10.3389/fimmu.2018.02408. PMID: 30405611; PMCID: PMC6204383.
  • Wurm AA, Tenen DG, Behre G. The Janus-faced Nature of miR-22 inHematopoiesis: Is It an Oncogenic Tumor Suppressor or Rather a Tumor-Suppressive Oncogene? PLoS Genet. 2017 Jan 12;13(1):e1006505. doi:10.1371/journal.pgen.1006505. PMID: 28081132; PMCID: PMC5230742.
  • Jentzsch M, Bill M, Nicolet D, Leiblein S, Schubert K, Pless M, Bergmann U,Wildenberger K, Schuhmann L, Cross M, Pönisch W, Franke GN, Vucinic V, Lange T,Behre G, Mrózek K, Bloomfield CD, Niederwieser D, Schwind S. Prognostic impactof the CD34+/CD38- cell burden in patients with acute myeloid leukemia receivingallogeneic stem cell ransplantation. Am J Hematol. 2017 Apr;92(4):388-396. doi:10.1002/ajh.24663. Epub 2017 Feb 21. PMID: 28133783.
  • Zjablovskaja P, Kardosova M, Danek P, Angelisova P, Benoukraf T, Wurm AA, Kalina T, Sian S, Balastik M, Delwel R, Brdicka T, Tenen DG, Behre G, Fiore F, Malissen B, Horejsi V, Alberich-Jorda M. EVI2B is a C/EBPα target gene required for granulocytic differentiation and functionality of hematopoietic progenitors. Cell Death Differ. 2017 Apr;24(4):705-716. doi: 10.1038/cdd.2017.6. Epub 2017 Feb 10. Erratum in: Cell Death Differ. 2019 Jan;26(1):198. PMID: 28186500; PMCID: PMC5384033.
  • Wurm AA, Zjablovskaja P, Kardosova M, Gerloff D, Bräuer-Hartmann D, Katzerke C, Hartmann JU, Benoukraf T, Fricke S, Hilger N, Müller AM, Bill M, Schwind S, Tenen DG, Niederwieser D, Alberich-Jorda M, Behre G. Disruption of the C/EBPα- miR-182 balance impairs granulocytic differentiation. Nat Commun. 2017 Jun 29;8(1):46. doi: 10.1038/s41467-017-00032-6. PMID: 28663557; PMCID: PMC5491528.
  • Jentzsch M, Bill M, Grimm J, Schulz J, Goldmann K, Beinicke S, Häntschel J, Pönisch W, Franke GN, Vucinic V, Behre G, Lange T, Niederwieser D, Schwind S. High <i>BAALC</i> copy numbers in peripheral blood prior to allogeneic transplantation predict early relapse in acute myeloid leukemia patients. Oncotarget. 2017 Sep 27;8(50):87944-87954. doi: 10.18632/oncotarget.21322. PMID: 29152132; PMCID: PMC5675684.
  • Mellinghoff SC, Panse J, Alakel N, Behre G, Buchheidt D, Christopeit M, Hasenkamp J, Kiehl M, Koldehoff M, Krause SW, Lehners N, von Lilienfeld-Toal M, Löhnert AY, Maschmeyer G, Teschner D, Ullmann AJ, Penack O, Ruhnke M, Mayer K, Ostermann H, Wolf HH, Cornely OA. Primary prophylaxis of invasive fungal infections in patients with haematological malignancies: 2017 update of the recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society for Haematology and Medical Oncology (DGHO). Ann Hematol. 2018 Feb;97(2):197-207. doi: 10.1007/s00277-017-3196-2. Epub 2017 Dec 7. PMID: 29218389; PMCID: PMC5754425.
  • Namasu CY, Katzerke C, Bräuer-Hartmann D, Wurm AA, Gerloff D, Hartmann JU, Schwind S, Müller-Tidow C, Hilger N, Fricke S, Christopeit M, Niederwieser D, Behre G. ABR, a novel inducer of transcription factor C/EBPα, contributes to myeloid differentiation and is a favorable prognostic factor in acute myeloid leukemia. Oncotarget. 2017 Oct 26;8(61):103626-103639. doi: 10.18632/oncotarget.22093. PMID: 29262589; PMCID: PMC5732755.
  • Nass N, Walter S, Jechorek D, Weissenborn C, Ignatov A, Haybaeck J, Sel S, Kalinski T. High neuronatin (NNAT) expression is associated with poor outcome in breast cancer. Virchows Arch. 2017 Jul;471(1):23-30. doi: 10.1007/s00428-017-2154-7. Epub 2017 May 24. PMID: 28540450.
  • Nass N, Bayreuther K, Simm A. Systemic activation of NF-κB driven luciferase activity in transgenic mice fed advanced glycation end products modified albumin. Glycoconj J. 2017 Apr;34(2):157-161. doi: 10.1007/s10719-017-9762-y. Epub 2017 Feb 13. PMID: 28194603.
  • Nass N, Trau S, Paulsen F, Kaiser D, Kalinski T, Sel S. The receptor for advanced glycation end products RAGE is involved in corneal healing. Ann Anat. 2017 May;211:13-20. doi: 10.1016/j.aanat.2017.01.003. Epub 2017 Feb 3. PMID: 28163201.
  • Weissenborn C, Ignatov T, Nass N, Kalinski T, Dan Costa S, Zenclussen AC, Ignatov A. GPER Promoter Methylation Controls GPER Expression in Breast Cancer Patients. Cancer Invest. 2017 Feb 7;35(2):100-107. doi: 10.1080/07357907.2016.1271886. Epub 2017 Jan 24. PMID: 28118074.
  • Sel S, Patzel E, Poggi L, Kaiser D, Kalinski T, Schicht M, Paulsen F, Nass N. Temporal and spatial expression pattern of Nnat during mouse eye development. Gene Expr Patterns. 2017 Jan;23-24:7-12. doi: 10.1016/j.gep.2016.12.002. Epub 2016 Dec 27. PMID: 28038958.
  • Nass N, Ignatov A, Andreas L, Weißenborn C, Kalinski T, Sel S. Accumulation of the advanced glycation end product carboxymethyl lysine in breast cancer is positively associated with estrogen receptor expression and unfavorable prognosis in estrogen receptor-negative cases. Histochem Cell Biol. 2017 May;147(5):625-634. doi: 10.1007/s00418-016-1534-4. Epub 2016 Dec 23. PMID: 28012130.
  • Nass N, Streit S, Wybranski C, Jürgens J, Brauner J, Schulz N, Powerski M, Ricke J, Kalinski T, Dudeck O, Seidensticker M. Validation of VX2 as a Hepatocellular Carcinoma Model: Comparison of the Molecular Reaction of VX2 and HepG2 Tumor Cells to Sorafenib In Vitro. Anticancer Res. 2017 Jan;37(1):87-93. doi: 10.21873/anticanres.11293. PMID: 28011478.