Wissenschaftliche Publikationen

  • Impact of tumour volume and treatment delay on the outcome after linear accelerator-based fractionated stereotactic radiosurgery of uveal melanoma. Sreenivasa S, Wösle M, Gager Y, Vordermark D, Grajewski L, Krause L, Ciernik IF. Br J Ophthalmol. 2023 Mar 9:bjo-2022-322750. doi: 10.1136/bjo-2022-322750. Online ahead of print. PMID: 36894300 Free article.

  • Evaluation of radiodensity and dimensional stability of polymeric materials used for oral stents during external beam radiotherapy of head and neck carcinomas. Jonovic K, Özcan M, Al-Haj Husain N, Mätzener KJ, Ciernik IF. Clin Transl Radiat Oncol. 2022 Jun 18;36:31-39. doi: 10.1016/j.ctro.2022.06.006. eCollection 2022 Sep. PMID: 35762007 Free PMC article.

  • Stereotactic body radiotherapy of adrenal metastases-A dose-finding study. Buergy D, Würschmidt F, Gkika E, Hörner-Rieber J, Knippen S, Gerum S, Balermpas P, Henkenberens C, Voglhuber T, Kornhuber C, Barczyk S, Röper B, Rashid A, Blanck O, Wittig A, Herold HU, Brunner TB, Sweeney RA, Kahl KH, Ciernik IF, Ottinger A, Izaguirre V, Putz F, König L, Hoffmann M, Combs SE, Guckenberger M, Boda-Heggemann J. Int J Cancer. 2022 Aug 1;151(3):412-421. doi: 10.1002/ijc.34017. Epub 2022 Apr 13. PMID: 35383919 Free article.

  • Dental extraction, intensity-modulated radiotherapy of head and neck cancer, and osteoradionecrosis : A systematic review and meta-analysis. Balermpas P, van Timmeren JE, Knierim DJ, Guckenberger M, Ciernik IF. Strahlenther Onkol. 2022 Mar;198(3):219-228. doi: 10.1007/s00066-021-01896-w. Epub 2022 Jan 14. PMID: 35029717 Free PMC article. Review.

  • Changes of healthy brain tissue after salvage radiotherapy of glioblastoma. de la Cruz L, Chen X, Konugoglu E, Ciernik IF. Neurooncol Adv. 2021 Sep 20;3(1):vdab139. doi: 10.1093/noajnl/vdab139. eCollection 2021 Jan-Dec. PMID: 34901856 Free PMC article.

  • Feasibility of aponeurectomy in combination with perioperative 192Ir high dose rate brachytherapy for Dupuytren's disease.  Ciernik IF, Goldschmidt P, Wösle M, Winter J. Strahlenther Onkol. 2021 Oct;197(10):903-908. doi: 10.1007/s00066-021-01801-5. Epub 2021 Sep 7. PMID: 34491382

  • Stereotactic or conformal radiotherapy for adrenal metastases: Patient characteristics and outcomes in a multicenter analysis. Buergy D, Würschmidt F, Gkika E, Hörner-Rieber J, Knippen S, Gerum S, Balermpas P, Henkenberens C, Voglhuber T, Kornhuber C, Barczyk S, Röper B, Rashid A, Blanck O, Wittig A, Herold HU, Brunner TB, Klement RJ, Kahl KH, Ciernik IF, Ottinger A, Izaguirre V, Putz F, König L, Hoffmann M, Combs SE, Guckenberger M, Boda-Heggemann J. Int J Cancer. 2021 Jul 15;149(2):358-370. doi: 10.1002/ijc.33546. Epub 2021 Mar 25. PMID: 33682927

  • Anti-cancer agent 3-bromopyruvate reduces growth of MPNST and inhibits metabolic pathways in a representative in-vitro model. Linke C, Wösle M, Harder A. BMC Cancer. 2020 Sep 18;20(1):896. doi: 10.1186/s12885-020-07397-w. PMID: 32948135 Free PMC article.

  • Salvage radiation therapy for patients with relapsing glioblastoma multiforme and the role of slow fractionation.  Ciernik IF, Gager Y, Renner C, Spieker S, Arndt N, Neumann K. FRONTIERS IN ONCOLOGY (in press; 2020)
     
  •  Treatment of radiation-induced maculopathy with fluocinolone acetonide.  Zimmermann L, Kneifel C, Grajewski L, Ciernik IF, Krause L. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY 258:2535-2539 (2020) DOI:10.1007/s00417-020-04804-7
     
  • The superficially averaged dose gradient at the target volume's boundary: A two-dimensional formulation and solution of anisotropic dose gradient problems.  Wösle M. ZEITSCHRIFT FUR MEDIZINISCHE PHYSIK 30(1):70-86 (2020)
     

  • Salvage Radiation Therapy for Patients With Relapsing Glioblastoma Multiforme and the Role of Slow Fractionation. Ciernik IF, Gager Y, Renner C, Spieker S, Arndt N, Neumann K. Front Oncol. 2020 Dec 8;10:577443. doi: 10.3389/fonc.2020.577443. eCollection 2020. PMID: 33364191 Free PMC article.

  • Treatment of radiation-induced maculopathy with fluocinolone acetonide. Zimmermann L, Kneifel C, Grajewski L, Ciernik IF, Krause L. Graefes Arch Clin Exp Ophthalmol. 2020 Nov;258(11):2535-2539. doi: 10.1007/s00417-020-04804-7. Epub 2020 Jul 14. PMID: 32661701

  • The superficially averaged dose gradient at the target volume's boundary: A two-dimensional formulation and solution of anisotropic dose gradient problems. Wösle M. Z Med Phys. 2020 Feb;30(1):70-86. doi: 10.1016/j.zemedi.2019.09.002. Epub 2019 Dec 14. PMID: 31843265

  • Pattern of failure after adjuvant radiotherapy following extrapleural pneumonectomy of pleural mesothelioma in the SAKK 17/04 trial. Riesterer O, Ciernik IF, Stahel RA, Xyrafas A, Aebersold DM, Plasswilm L, Mahmut Ozsahin E, Zwahlen DR, Nackaerts K, Zimmermann F, Sabrina Stark L, Weder W, Krayenbuehl J; Swiss Group for Clinical Cancer Research (SAKK). Radiother Oncol. 2019 Sep;138:121-125. doi: 10.1016/j.radonc.2019.05.024. Epub 2019 Jun 25. PMID: 31252293 Clinical Trial.

  • Visualization of the tumor cavity after lumpectomy of breast cancer for postoperative radiotherapy. Ciernik IF, Greiss AM. Clin Transl Radiat Oncol. 2018 Nov 23;14:47-50. doi: 10.1016/j.ctro.2018.11.003. eCollection 2019 Jan. PMID: 30555941 Free PMC article.

  • Stereotactic radiotherapy for choroidal melanomas by means of HybridArc™ : Physics and technique of linac-based photon beam therapy. Wösle M, Krause L, Sreenivasa S, Vordermark D, Ciernik IF. Strahlenther Onkol. 2018 Oct;194(10):929-943. doi: 10.1007/s00066-018-1349-4. Epub 2018 Aug 16. PMID: 30116827 English.

  • Optimizing radiosurgery with photons for ocular melanoma. Ciernik IF, Wösle M, Krause L, Krayenbuehl J. Phys Imaging Radiat Oncol. 2018 Jun 19;6:83-88. doi: 10.1016/j.phro.2018.06.001. eCollection 2018 Apr. PMID: 33458394 Free PMC article.

  • Anti-cancer agent 3-bromopyruvate reduces growth of MPNST and inhibits metabolic pathways in a representative in-vitro model. Linke C, Wösle M, Harder A. BMC CANCER 20(1): 896 (2020) DOI: 10.1186/s12885-020-07397-w
     
  • Visualization of the tumor cavity after lumpectomy of breast cancer for postoperative radiotherapy.    Ciernik IF, Greiss AM. CLINICAL AND TRANSLATIONAL RADIATION ONCOLOGY 14:47-50 (2019) DOI: 10.1016/j.ctro.2018.11.003
     
  • Pattern of failure after adjuvant radiotherapy following extrapleural pneumonectomy of pleural mesothelioma in the SAKK 17/04 trial. Riesterer O, Ciernik IF, Stahel RA, Xyrafas A, Aebersold DM, Plasswilm L, Ozsahin EM, Zwahlen DR, Nackaerts K, Zimmermann F, ; Stark, LS, Weder W, Krayenbuehl J, Swiss Grp Clinical Canc Res SAKK. RADIOTHERAPY AND ONCOLOGY 138:121-125 (2019) DOI: 10.1016/j.radonc.2019.05.024
     
  • Stereotactic radiotherapy for choroidal melanomas by means of HybridArc (TM).  Wosle M, Krause L, Sreenivasa S, vordermark D, Ciernik IF. STRAHLENTHERAPIE UND ONKOLOGIE 194(10):929-943 (2018) DOI: 10.1007/s00066-018-1349-4
     
  • Optimizing radiosurgery with photons for ocular melanoma. Ciernik IF, Wösle M, Krause L, Krayenbuehl K.  PHYSICS AND IMAGING IN RADIATION ONCOLOGY 6:83-88 (2018); doi.org/10.1016/j.phro.2018.06.001
     
  • External beam radiotherapy for unresectable hepatocellular carcinoma, an international multicenter phase I trial, SAKK 77/07 and SASL 26. Herrmann E, Naehirg D, Sassowsky M, Bigler M, Buijsen J, Ciernik I, Zwahlen D, Pellanda Frenzetti AF, Meister A, Brauchli P, Berardi S, Kuettel E, Dufour JF, Aebersold DM. RADIATION ONCOLOGY 12:12 (2017); DOI: 10.1186/s13014-016-0745-0
     
  • External beam radiotherapy for unresectable hepatocellular carcinoma, an international multicenter phase I trial, SAKK 77/07 and SASL 26. Herrmann E, Naehrig D, Sassowsky M, Bigler M, Buijsen J, Ciernik I, Zwahlen D, Pellanda AF, Meister A, Brauchli P, Berardi S, Kuettel E, Dufour JF, Aebersold DM; Swiss Group for Clinical Cancer Research (SAKK). Radiat Oncol. 2017 Jan 13;12(1):12. doi: 10.1186/s13014-016-0745-0. PMID: 28086942 Free PMC article. Clinical Trial.
     
  • Neoadjuvant chemotherapy and extrapleural pneumonectomy of malignant pleural mesothelioma with or without hemithoracic radiotherapy (SAKK 17/04): a randomised, international, multicentre phase 2 trial. Stahel RA, Riesterer O, Xyrafas A, Opitz I, Beyeler M, Ochsenbein A, Fruh M, Cathomas R, Nackaerts K, Peters S, Mamot C, Zippelius A, Mordasini C, Caspar CB, Eckhardt K, Schmid RA, Aebersold DM, Gautschi O, Nagel W, Topfer M, Krayenbuehl J, Ribi K, Ciernik IF, Weder W. LANCET ONCOLOGY 16(16): 1651-1658 (2015); DOI: 10.1016/S1470-2045(15)00208-9
     
  • Standardization of the Target Volume for Boost or Partial Breast Radiation Therapy After Lumpectomy of Breast Cancer. Ciernik IF, Voss H, Wösle M. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 89(3):690-691 (2014); DOI: 10.1016/j.ijrobp.2014.02.037
     
  • Clinical outcome of postoperative highly conformal versus 3D conformal radiotherapy in patients with malignant pleural mesothelioma.  Krayenbuehl J, Dimmerling P, Ciernik IF, Riesterer O.    RADIATION ONCOLOGY 9:32 (2014) DOI:10.1186/1748-717X-9-32
     
  • Intensity-modulated radiotherapy and volumetric-modulated arc therapy for malignant pleural mesothelioma after extrapleural pleuropneumonectomy.  Krayenbuehl J, Riesterer O, Graydon S, Dimmerling P, Kloeck S, Ciernik IF.  JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS 14(4):36-45 (2013)
     
  • Hierarchical enhanced non-rigid registration for target volume correction and propagation for adaptive external beam radiotherapy of carcinoma of the prostate.  Andronache A, Krayenbuehl J, Szekely G, Ciernik IF. JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS 14(5):222-230 (2013) DOI: 10.1120/jacmp.v14i5.4374
     
  • Evaluation of different external radiation therapy techniques for the treatment of malignant pleural mesothelioma after extrapleural pleuropneumonectomy.  Krayenbuehl J, Hartmann M, Riesterer O, Lomax T, Kloeck S, Hug E, Ciernik IF. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 83(3):S866-S866(2012) DOI: 10.1016/j.ijrobp.2012.07.2316
     
  • Evaluation of the dosimetric impact of interfractional anatomical variations on prostate proton therapy using daily in-room CT images. Wang Y, Efstathiou JA, Sharp GC, Lu HM, Ciernik IF, Trofimov AV MEDICAL PHYSICS 38(8) 4623-4633 (2011) DOI: 10.1118/1.3604152
     
  • Proton-Based Radiotherapy for Unresectable or Incompletely Resected Osteosarcoma.  Ciernik IF, Niemierko A, Harmon DC, Kobayashi W,  Chen YL, Yock TI, Ebb DH, Choy E, Raskin KA, Liebsch N, Hornicek FJ, DeLaneyTF. CANCER 117(19):4522-4530 (2011) DOI: 10.1002/cncr.26037
     
  • Gefitinib in combination with irradiation with or without cisplatin in patients with inopreable Stage III non-small cell lung cancer: a phase I trial. Rothschild S, Bucher SE, Bernier J, Aebersold DM, Zouhair A, Ries G, Lombrieser N, Lippuner T, Lutolf UM, Glanzmann C, Ciernik IF.     INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS Volume: 80 (1):126-132 (2011) DOI: 10.1016/j.ijrobp.2010.01.048
     
  • Chemo-radiation with or without mandatory split in anal carcinoma: experiences of two institutions and review of the literature.  Oehler C, Provencher S, Donath D, Bahary JP, Lutolf UM, Ciernik IF.    RADIATION ONCOLOGY 5:36 (2010) DOI: 10.1186/1748-717X-5-36